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Trituration Definition

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Trituration Definition. The act or process of triturating. Medical definition of trituration.

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The act of reducing a drug to a fine powder and incorporating it thoroughly with sugar of milk lactose by rubbing the two together in a mortar. One containing a pulverized mixture of a medicinal substance with lactose. A solvent is chosen in which the desired product is insoluble and the undesired by products are very soluble or vice versa.

The state of being triturated.

Trituration can be defined as the purification of an impure compound by taking advantage of the solubility differences of the compound vs its impurities in a solvent or solvent mixture. Mixing of dental amalgam in a mortar and pestle or with a mechanical device. In organic chemistry trituration is a process used to purify crude chemical compounds containing soluble impurities. Trituration is the name of several different methods of processing materials.

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